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BDBM50193697 CHEMBL217751::N-(2-aminoquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide

SMILES: Nc1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1

InChI Key: InChIKey=AAOYBQGKRBCNLH-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193697   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM50193697
PNG
(CHEMBL217751 | N-(2-aminoquinolin-6-yl)-3-(4-(trif...)
Show SMILES Nc1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1
Show InChI InChI=1S/C19H16F3N3O/c20-19(21,22)14-5-1-12(2-6-14)3-10-18(26)24-15-7-8-16-13(11-15)4-9-17(23)25-16/h1-2,4-9,11H,3,10H2,(H2,23,25)(H,24,26)
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GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 240n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of 125I-[Phe13,Tyr19]-MCH from human MCH-R1


Bioorg Med Chem Lett 16: 5270-4 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.006
BindingDB Entry DOI: 10.7270/Q2ZC82HP
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50193697
PNG
(CHEMBL217751 | N-(2-aminoquinolin-6-yl)-3-(4-(trif...)
Show SMILES Nc1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1
Show InChI InChI=1S/C19H16F3N3O/c20-19(21,22)14-5-1-12(2-6-14)3-10-18(26)24-15-7-8-16-13(11-15)4-9-17(23)25-16/h1-2,4-9,11H,3,10H2,(H2,23,25)(H,24,26)
Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 720n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Stimulation of IP3-coupled mobilization of calcium in HEK293 cells expressing rat MCH-R1


Bioorg Med Chem Lett 16: 5270-4 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.006
BindingDB Entry DOI: 10.7270/Q2ZC82HP
More data for this
Ligand-Target Pair