BindingDB PrimarySearch_ki

Search and Browse
- Target
- Compound
- Special tools
- Citation
- Special Data Sets
- Other Databases
  - PDB 85% 100% Seq ID
  - UniProtKB/Swiss-Prot
  - UniProtKB/TrEMBL
  - PubMed
Download
- All Compounds & Data
- Target Names &
  - Ki IC50 Kd EC50
  - ΔG° ΔH° -TΔS°
Enter Data

BDBM50196143 4-(3,4-dimethylpiperazin-1-yl)phenyl]-(3-ethyl-2-methyl-5,6,7,8-tetrahydroquinolin-4-yl)amine::CHEMBL217768

SMILES: CCc1c(C)nc2CCCCc2c1Nc1ccc(cc1)N1CCN(C)C(C)C1

InChI Key: InChIKey=AWRXNUNJSQSZSP-UHFFFAOYSA-N

Data: 4 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50196143
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Alpha-2C adrenergic receptor (Human)	BDBM50196143 (4-(3,4-dimethylpiperazin-1-yl)phenyl]-(3-ethyl-2-m...) Show SMILES Show InChI	GoogleScholar	UniChem		110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Human)	BDBM50196143 (4-(3,4-dimethylpiperazin-1-yl)phenyl]-(3-ethyl-2-m...) Show SMILES Show InChI	GoogleScholar	UniChem		110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Human)	BDBM50196143 (4-(3,4-dimethylpiperazin-1-yl)phenyl]-(3-ethyl-2-m...) Show SMILES Show InChI	GoogleScholar	UniChem		630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Human)	BDBM50196143 (4-(3,4-dimethylpiperazin-1-yl)phenyl]-(3-ethyl-2-m...) Show SMILES Show InChI	GoogleScholar	UniChem		2.98E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair