BDBM50196289 6-(4-methoxyphenyl)-5-methyl-3-phenylisoxazolo[4,5-c]pyridin-4(5H)-one::CHEMBL399602

SMILES COc1ccc(cc1)-c1cc2onc(-c3ccccc3)c2c(=O)n1C

InChI Key InChIKey=QCKTZIBCJPYKHO-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50196289   

TargetNuclear receptor subfamily 4 group A member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50196289(6-(4-methoxyphenyl)-5-methyl-3-phenylisoxazolo[4,5...)
Affinity DataEC50:  4.10nMAssay Description:Activation of Nurr1 expressed in MN9D cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50196289(6-(4-methoxyphenyl)-5-methyl-3-phenylisoxazolo[4,5...)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed