BDBM50197423 CHEMBL3925899
SMILES CC(=S)NCCCC[C@@H]1NC(=O)[C@H](Cc2csc3ccccc23)NC(=O)CCCCCCC(=O)NCCCC[C@H](NC1=O)C(N)=O
InChI Key InChIKey=ZTIGWNUKJZSQFN-QKDODKLFSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50197423
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University
Curated by ChEMBL
Jiangsu University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human GST or His6-tagged SIRT1 using H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH as substrate incubated for 10 mins in presence...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
Jiangsu University
Curated by ChEMBL
Jiangsu University
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant human His6-tagged SIRT6 using H2N-EALPK-[Nepsilon-myristoyl-lysine]-TGGPQ-CONH2 as substrate incubated for 12 mins in prese...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Jiangsu University
Curated by ChEMBL
Jiangsu University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged SIRT5 using CH3CONH-AR-[Nepsilon-succinyl-lysine]-ST-CONH2 as substrate incubated for 5 mins in presence o...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Jiangsu University
Curated by ChEMBL
Jiangsu University
Curated by ChEMBL
Affinity DataIC50: 3.82E+3nMAssay Description:Inhibition of recombinant human His6-tagged SIRT3 using H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH as substrate incubated for 10 mins in presence of bet...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Jiangsu University
Curated by ChEMBL
Jiangsu University
Curated by ChEMBL
Affinity DataIC50: 890nMAssay Description:Inhibition of recombinant human His6-tagged SIRT2 using H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH as substrate incubated for 12 mins in presence of bet...More data for this Ligand-Target Pair