BDBM50197423 CHEMBL3925899

SMILES CC(=S)NCCCC[C@@H]1NC(=O)[C@H](Cc2csc3ccccc23)NC(=O)CCCCCCC(=O)NCCCC[C@H](NC1=O)C(N)=O

InChI Key InChIKey=ZTIGWNUKJZSQFN-QKDODKLFSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50197423   

TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50197423(CHEMBL3925899)
Affinity DataIC50:  500nMAssay Description:Inhibition of recombinant human GST or His6-tagged SIRT1 using H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH as substrate incubated for 10 mins in presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50197423(CHEMBL3925899)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant human His6-tagged SIRT6 using H2N-EALPK-[Nepsilon-myristoyl-lysine]-TGGPQ-CONH2 as substrate incubated for 12 mins in prese...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50197423(CHEMBL3925899)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged SIRT5 using CH3CONH-AR-[Nepsilon-succinyl-lysine]-ST-CONH2 as substrate incubated for 5 mins in presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50197423(CHEMBL3925899)
Affinity DataIC50:  3.82E+3nMAssay Description:Inhibition of recombinant human His6-tagged SIRT3 using H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH as substrate incubated for 10 mins in presence of bet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50197423(CHEMBL3925899)
Affinity DataIC50:  890nMAssay Description:Inhibition of recombinant human His6-tagged SIRT2 using H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH as substrate incubated for 12 mins in presence of bet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed