BDBM50197470 (1S,2S,3S,7R)-methyl 3-(3,4-dichlorophenyl)-7-hydroxy-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate::CHEMBL227773

SMILES COC(=O)[C@@H]1[C@H]2[C@H](O)CC(C[C@@H]1c1ccc(Cl)c(Cl)c1)N2C

InChI Key InChIKey=BGWLJJSQLYVDMU-RHJZULMUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50197470   

TargetSodium-dependent dopamine transporter(Macaca fascicularis)
Organix

Curated by ChEMBL
LigandPNGBDBM50197470((1S,2S,3S,7R)-methyl 3-(3,4-dichlorophenyl)-7-hydr...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [3H]WIN 35428 from DAT in rhesus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Macaca mulatta)
Organix

Curated by ChEMBL
LigandPNGBDBM50197470((1S,2S,3S,7R)-methyl 3-(3,4-dichlorophenyl)-7-hydr...)
Affinity DataIC50:  15nMAssay Description:Displacement of [3H]citalopram from SERT in rhesus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed