BDBM50197902 CHEMBL225492::N-(1-(4-chlorobenzyl)piperidin-3-yl)isoquinolin-5-amine::N-[1-(4-chlorobenzyl)-3-piperidyl]-N-(5-isoquinolyl)amine

SMILES Clc1ccc(CN2CCCC(C2)Nc2cccc3cnccc23)cc1

InChI Key InChIKey=AHBYTGBWKOEDEE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50197902   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50197902(CHEMBL225492 | N-(1-(4-chlorobenzyl)piperidin-3-yl...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of MCP1-induced chemotaxis in U937 cells overexpressing CCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1/2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50197902(CHEMBL225492 | N-(1-(4-chlorobenzyl)piperidin-3-yl...)
Affinity DataIC50:  185nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed