BDBM50198114 CHEMBL231150::N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-4-[(1S,5'R)-5'-methylspiro[indene-1,4'-piperidine]-1'-yl]-2-[2-(2-phenylpropanamido)-1,3-thiazol-4-yl]butanamide

SMILES CC(C(=O)Nc1nc(cs1)C(CCN1CC[C@]2(C=Cc3ccccc23)[C@@H](C)C1)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1ccccc1

InChI Key InChIKey=JWKLHPJIQARGDH-NYQRLVHPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198114   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198114(CHEMBL231150 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  74nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198114(CHEMBL231150 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  517nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed