BDBM50198114 CHEMBL231150::N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-4-[(1S,5'R)-5'-methylspiro[indene-1,4'-piperidine]-1'-yl]-2-[2-(2-phenylpropanamido)-1,3-thiazol-4-yl]butanamide
SMILES CC(C(=O)Nc1nc(cs1)C(CCN1CC[C@]2(C=Cc3ccccc23)[C@@H](C)C1)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1ccccc1
InChI Key InChIKey=JWKLHPJIQARGDH-NYQRLVHPSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50198114
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 517nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 expressed in monocytesMore data for this Ligand-Target Pair