BDBM50198119 CHEMBL231340::N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-4-[(1S,5'R)-5'-methylspiro[indene-1,4'-piperidine]-1'-yl]-2-{2-[2-(pyridin-2-yl)acetamido]-1,3-thiazol-4-yl}butanamide

SMILES C[C@H]1CN(CCC(C(=O)NCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2csc(NC(=O)Cc3ccccn3)n2)CC[C@]11C=Cc2ccccc12

InChI Key InChIKey=AAMCCXZHVCUGJS-KEHMHDMQSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198119   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198119(CHEMBL231340 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  13nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198119(CHEMBL231340 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  79nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed