BDBM50200885 (R)-3-(2-(1-(3-fluorophenyl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide::CHEMBL401512

SMILES CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cccc(F)c1

InChI Key InChIKey=DRBFDAYBUUMUHY-OAHLLOKOSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50200885   

TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50200885((R)-3-(2-(1-(3-fluorophenyl)propylamino)-3,4-dioxo...)
Affinity DataIC50:  4.90nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200885((R)-3-(2-(1-(3-fluorophenyl)propylamino)-3,4-dioxo...)
Affinity DataIC50:  197nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR1 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50200885((R)-3-(2-(1-(3-fluorophenyl)propylamino)-3,4-dioxo...)
Affinity DataIC50:  4.90nMAssay Description:Displacement of [125I]hCXCL8 from human CXCR2 receptor expressed in BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50200885((R)-3-(2-(1-(3-fluorophenyl)propylamino)-3,4-dioxo...)
Affinity DataIC50:  4.90nMAssay Description:Displacement of [125I]IL8 from human CXCR2 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed