BDBM50201575 CHEMBL3903475

SMILES Cc1cn(cn1)-c1ccc(cc1F)-c1cn(CC(=O)Nc2cccc(Cl)c2Cl)nn1

InChI Key InChIKey=PRSMZNFUKBHAIS-UHFFFAOYSA-N

Data  5 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50201575   

TargetProbable G-protein coupled receptor 142(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50201575(CHEMBL3903475)
Affinity DataEC50:  78nMAssay Description:Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 to 5 mins by Fluo-4AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50201575(CHEMBL3903475)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human GPR142 expressed in CHO cells measured after 30 to 60 mins by IP-One assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50201575(CHEMBL3903475)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50201575(CHEMBL3903475)
Affinity DataEC50:  9nMAssay Description:Agonist activity at mouse GPR142 expressed in CHO cells measured after 30 to 60 mins by IP-One assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50201575(CHEMBL3903475)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Cav1.2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50201575(CHEMBL3903475)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50201575(CHEMBL3903475)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50201575(CHEMBL3903475)
Affinity DataEC50:  38nMAssay Description:Agonist activity at human GPR142 expressed in CHO cells measured for 3 to 5 mins by Fluo-4AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50201575(CHEMBL3903475)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed