BDBM50201658 (E)-1-(4-chlorothiophen-3-yl)-3-(1-methyl-4-oxoimidazolidin-2-ylidene)urea::CHEMBL391604

SMILES Cn1cc(O)nc1NC(=O)Nc1csc(Cl)c1

InChI Key InChIKey=ASCXDIFMPALKNB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201658   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50201658((E)-1-(4-chlorothiophen-3-yl)-3-(1-methyl-4-oxoimi...)
Affinity DataIC50:  78nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50201658((E)-1-(4-chlorothiophen-3-yl)-3-(1-methyl-4-oxoimi...)
Affinity DataIC50:  434nMAssay Description:Antagonist activity at mGluR5 by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed