BDBM50202528 8-Cyclopentyl-6-ethyl-3-thiophen-2-yl-5,8-dihydro-4H-1,2,3a,7,8-pentaaza-as-indacene::9-cyclopentyl-5,6-dihydro-7-ethyl-3-(thien-2-yl)-9H-pyrazolo[3,4-c]-1,2,4-triazolo[4,3-alpha]pyridine::CHEMBL217899

SMILES CCc1nn(C2CCCC2)c-2c1CCn1c(nnc-21)-c1cccs1

InChI Key InChIKey=DHCOPPHTVOXDKU-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50202528   

TargetAdenosine receptor A1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50202528(8-Cyclopentyl-6-ethyl-3-thiophen-2-yl-5,8-dihydro-...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50202528(8-Cyclopentyl-6-ethyl-3-thiophen-2-yl-5,8-dihydro-...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50202528(8-Cyclopentyl-6-ethyl-3-thiophen-2-yl-5,8-dihydro-...)
Affinity DataIC50: >100nMAssay Description:Inhibition of human recombinant PDE4CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50202528(8-Cyclopentyl-6-ethyl-3-thiophen-2-yl-5,8-dihydro-...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50202528(8-Cyclopentyl-6-ethyl-3-thiophen-2-yl-5,8-dihydro-...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50202528(8-Cyclopentyl-6-ethyl-3-thiophen-2-yl-5,8-dihydro-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50202528(8-Cyclopentyl-6-ethyl-3-thiophen-2-yl-5,8-dihydro-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50202528(8-Cyclopentyl-6-ethyl-3-thiophen-2-yl-5,8-dihydro-...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed