BDBM50203985 (E)-1-(2,4-dihydroxyphenyl)-3-(2,4-dihydroxyphenyl)-2-propen-1-one (18)::2,2',4,4'-tetrahydroxychalcone::2,4,2',4'-tetrahydroxychalcone::CHEMBL394855

SMILES: Oc1ccc(\C=C\C(=O)c2ccc(O)cc2O)c(O)c1

InChI Key: InChIKey=ZWTDXYUDJYDHJR-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50203985   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Human)	BDBM50203985 (2,2',4,4'-tetrahydroxychalcone | 2,4,2',4'-tetrahy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	620	n/a	n/a	n/a	n/a	4.5	37
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Aldo-keto reductase family 1 member B1 (Rat)	BDBM50203985 (2,2',4,4'-tetrahydroxychalcone | 2,4,2',4'-tetrahy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
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Polyphenol oxidase 2 (White button mushroom)	BDBM50203985 (2,2',4,4'-tetrahydroxychalcone | 2,4,2',4'-tetrahy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosinase (Human)	BDBM50203985 (2,2',4,4'-tetrahydroxychalcone | 2,4,2',4'-tetrahy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosinase (Mouse)	BDBM50203985 (2,2',4,4'-tetrahydroxychalcone | 2,4,2',4'-tetrahy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosinase (Human)	BDBM50203985 (2,2',4,4'-tetrahydroxychalcone | 2,4,2',4'-tetrahy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosinase (Mouse)	BDBM50203985 (2,2',4,4'-tetrahydroxychalcone | 2,4,2',4'-tetrahy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Polyphenol oxidase 2 (White button mushroom)	BDBM50203985 (2,2',4,4'-tetrahydroxychalcone | 2,4,2',4'-tetrahy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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