BDBM50207768 (4-methyl-piperazin-1-yl)-(3-p-tolyl-adamantan-1-yl)-methanone::CHEMBL246338::cid_2882437

SMILES CN1CCN(CC1)C(=O)C12CC3CC(C1)CC(C3)(C2)c1ccc(C)cc1

InChI Key InChIKey=CMXBQJXVKBWQCN-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50207768   

TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50207768((4-methyl-piperazin-1-yl)-(3-p-tolyl-adamantan-1-y...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207768((4-methyl-piperazin-1-yl)-(3-p-tolyl-adamantan-1-y...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
University Of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50207768((4-methyl-piperazin-1-yl)-(3-p-tolyl-adamantan-1-y...)
Affinity DataIC50:  81nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells after 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed