BDBM50208108 CHEMBL3954140::US9708270, 33

SMILES OC(=O)CC1CCC2(CC1)CCN(CC2)c1cc(ccn1)C(F)(F)F

InChI Key InChIKey=GCHINJJAFUYXMP-UHFFFAOYSA-N

Data  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50208108   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208108(CHEMBL3954140 | US9708270, 33)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GPR40 expressed in HEK293 cells assessed as induction of IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 4(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50208108(CHEMBL3954140 | US9708270, 33)
Affinity DataEC50:  4.20E+3nMAssay Description:Agonist activity at mouse GPR120 expressed in U2OS cells assessed as induction of beta-arrestin2 recruitment after 90 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208108(CHEMBL3954140 | US9708270, 33)
Affinity DataEC50:  3.10E+3nMAssay Description:Agonist activity at human GPR120 short isoform expressed in CHOK1 cells assessed as induction of IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208108(CHEMBL3954140 | US9708270, 33)
Affinity DataEC50:  3.06E+3nMAssay Description:On the day before the measurement day, CHO cells expressing human GPR120 were plated at 10000 cells per well in a 384-well black plate (#3702, Cornin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208108(CHEMBL3954140 | US9708270, 33)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GPR40 expressed in HEK293 cells assessed as induction of IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208108(CHEMBL3954140 | US9708270, 33)
Affinity DataEC50:  9.20E+3nMAssay Description:Agonist activity at ARMS2-PK2 -tagged human GPR120 short isoform expressed in CHOK1 cells assessed as induction of beta-arrestin2 recruitment after 9...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 4(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50208108(CHEMBL3954140 | US9708270, 33)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at mouse GPR120 expressed in CHOK1 cells assessed as induction of IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed