BDBM50208611 (2S)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-[(2R)-5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl]-2,3-dihydro-4H-chromen-4-one::CHEMBL243148::sophoraflavanone G
SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6@H](-[#6]-c1c(-[#8])cc(-[#8])c2-[#6](=O)-[#6]-[#6@H](-[#8]-c12)-c1ccc(-[#8])cc1-[#8])-[#6](-[#6])=[#6]
InChI Key InChIKey=XRYVAQQLDYTHCL-CMJOXMDJSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50208611
TargetBeta-secretase 1(Homo sapiens (Human))
Gyeongsang National University School Of Medicine
Curated by ChEMBL
Gyeongsang National University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of human SGLT1 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human SGLT2 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptakeMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibition of ABCG2 in becatecarin-selected ABCG2-overexpressing human A549/Bec150 cells assessed as increase in intracellular mitoxantrone accumulat...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
University Of Toyama
Curated by ChEMBL
University Of Toyama
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells assessed as suppression of T-current amplitude after 10 mins by whole cell patch clamp methodMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 2.12E+3nMAssay Description:Inhibition of ABCG2 in mitoxantrone-selected ABCG2-overexpressing human NCI-H460/MX20 cells assessed as increase in intracellular mitoxantrone accumu...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
University Of Toyama
Curated by ChEMBL
University Of Toyama
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human CaV3.1 expressed in HEK293 cells assessed as suppression of T-current after 10 mins by whole cell patch clamp methodMore data for this Ligand-Target Pair