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BDBM50210418 4-phenyl-1-(1-phenylhexyl)piperidin-4-ol::CHEMBL230253

SMILES: CCCCCC(N1CCC(O)(CC1)c1ccccc1)c1ccccc1

InChI Key: InChIKey=AHZUGQDNSYDLNN-UHFFFAOYNA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50210418   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nociceptin receptor


(Homo sapiens (Human))
BDBM50210418
PNG
(4-phenyl-1-(1-phenylhexyl)piperidin-4-ol | CHEMBL2...)
Show SMILES CCCCCC(N1CCC(O)(CC1)c1ccccc1)c1ccccc1
Show InChI InChI=1/C23H31NO/c1-2-3-6-15-22(20-11-7-4-8-12-20)24-18-16-23(25,17-19-24)21-13-9-5-10-14-21/h4-5,7-14,22,25H,2-3,6,15-19H2,1H3
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Article
PubMed
14n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding


Bioorg Med Chem Lett 17: 3023-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.061
BindingDB Entry DOI: 10.7270/Q24B3242
More data for this
Ligand-Target Pair
Cannabinoid receptor 1/Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50210418
PNG
(4-phenyl-1-(1-phenylhexyl)piperidin-4-ol | CHEMBL2...)
Show SMILES CCCCCC(N1CCC(O)(CC1)c1ccccc1)c1ccccc1
Show InChI InChI=1/C23H31NO/c1-2-3-6-15-22(20-11-7-4-8-12-20)24-18-16-23(25,17-19-24)21-13-9-5-10-14-21/h4-5,7-14,22,25H,2-3,6,15-19H2,1H3
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37n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranes


Bioorg Med Chem Lett 17: 3023-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.061
BindingDB Entry DOI: 10.7270/Q24B3242
More data for this
Ligand-Target Pair
Opioid receptors; mu/kappa/delta


(Homo sapiens (Human))
BDBM50210418
PNG
(4-phenyl-1-(1-phenylhexyl)piperidin-4-ol | CHEMBL2...)
Show SMILES CCCCCC(N1CCC(O)(CC1)c1ccccc1)c1ccccc1
Show InChI InChI=1/C23H31NO/c1-2-3-6-15-22(20-11-7-4-8-12-20)24-18-16-23(25,17-19-24)21-13-9-5-10-14-21/h4-5,7-14,22,25H,2-3,6,15-19H2,1H3
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184n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]diprenorphine from human DOP receptor expressed in CHO cell membranes


Bioorg Med Chem Lett 17: 3023-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.061
BindingDB Entry DOI: 10.7270/Q24B3242
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50210418
PNG
(4-phenyl-1-(1-phenylhexyl)piperidin-4-ol | CHEMBL2...)
Show SMILES CCCCCC(N1CCC(O)(CC1)c1ccccc1)c1ccccc1
Show InChI InChI=1/C23H31NO/c1-2-3-6-15-22(20-11-7-4-8-12-20)24-18-16-23(25,17-19-24)21-13-9-5-10-14-21/h4-5,7-14,22,25H,2-3,6,15-19H2,1H3
PDB

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220n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membranes


Bioorg Med Chem Lett 17: 3023-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.061
BindingDB Entry DOI: 10.7270/Q24B3242
More data for this
Ligand-Target Pair