BDBM50212369 CHEMBL537654::erythro-3,4-dichloromethylphenidate hydrochloride

SMILES COC(=O)[C@H]([C@H]1CCCCN1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=JUKMAYKVHWKRKY-OLZOCXBDSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50212369   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50212369(CHEMBL537654 | erythro-3,4-dichloromethylphenidate...)
Affinity DataKi:  363nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50212369(CHEMBL537654 | erythro-3,4-dichloromethylphenidate...)
Affinity DataKi:  2.57E+3nMAssay Description:Displacement of [3H]citalopram from 5HTT in Sprague-Dawley rat cerebrumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50212369(CHEMBL537654 | erythro-3,4-dichloromethylphenidate...)
Affinity DataIC50:  317nMAssay Description:Inhibition of [3H]DA uptake at DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed