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BDBM50212531 1-(4-chlorophenyl)-2-(phenylsulfonyl)ethanone::CHEMBL238834

SMILES: Clc1ccc(cc1)C(=O)CS(=O)(=O)c1ccccc1

InChI Key: InChIKey=KZACHGLUJYSTGQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212531   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
11-beta-hydroxysteroid dehydrogenase 2


(Homo sapiens (Human))
BDBM50212531
PNG
(1-(4-chlorophenyl)-2-(phenylsulfonyl)ethanone | CH...)
Show SMILES Clc1ccc(cc1)C(=O)CS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C14H11ClO3S/c15-12-8-6-11(7-9-12)14(16)10-19(17,18)13-4-2-1-3-5-13/h1-9H,10H2
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CHEMBL
PC cid
PC sid
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Similars

Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of human 11beta-HSD2 expressed in CHO cells


Bioorg Med Chem 15: 4396-405 (2007)


Article DOI: 10.1016/j.bmc.2007.04.035
BindingDB Entry DOI: 10.7270/Q24M95CG
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (Human))
BDBM50212531
PNG
(1-(4-chlorophenyl)-2-(phenylsulfonyl)ethanone | CH...)
Show SMILES Clc1ccc(cc1)C(=O)CS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C14H11ClO3S/c15-12-8-6-11(7-9-12)14(16)10-19(17,18)13-4-2-1-3-5-13/h1-9H,10H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of human 11beta-HSD1 expressed in CHO cells


Bioorg Med Chem 15: 4396-405 (2007)


Article DOI: 10.1016/j.bmc.2007.04.035
BindingDB Entry DOI: 10.7270/Q24M95CG
More data for this
Ligand-Target Pair