BDBM50215854 CHEMBL301829

SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(ccc1C(O)=O)C(F)(F)F

InChI Key InChIKey=NZQDWKCNBOELAI-KSFYIVLOSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50215854   

TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215854(CHEMBL301829)
Affinity DataIC50:  660nMAssay Description:Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophils in whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215854(CHEMBL301829)
Affinity DataIC50:  2nMAssay Description:Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215854(CHEMBL301829)
Affinity DataIC50:  2.40nMAssay Description:Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215854(CHEMBL301829)
Affinity DataIC50:  280nMAssay Description:Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215854(CHEMBL301829)
Affinity DataIC50:  6.80nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215854(CHEMBL301829)
Affinity DataIC50:  56nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215854(CHEMBL301829)
Affinity DataIC50:  56nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215854(CHEMBL301829)
Affinity DataIC50:  2nMAssay Description:Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed