BDBM50216051 2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)butyl)-1, 2-benzisothiazole-3(2H)-one 1,1-dioxide::CHEMBL238916

SMILES: FC(F)(F)c1cccc(c1)N1CCN(CCCCN2C(=O)c3ccccc3S2(=O)=O)CC1

InChI Key: InChIKey=BFNRVMJMTPNWFK-UHFFFAOYSA-N

Data: 18 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50216051   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rat)	BDBM50216051 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES Show InChI	GoogleScholar	UniChem		100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50216051 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES Show InChI	GoogleScholar	UniChem		100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Rat)	BDBM50216051 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES Show InChI	GoogleScholar	UniChem		100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50216051 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES Show InChI	GoogleScholar	UniChem		107	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50216051 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES Show InChI	GoogleScholar	UniChem		107	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50216051 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES Show InChI	GoogleScholar	UniChem		113	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50216051 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES Show InChI	GoogleScholar	UniChem		113	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM50216051 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES Show InChI	GoogleScholar	UniChem		113	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Human)	BDBM50216051 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES Show InChI	GoogleScholar	UniChem		1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(1B) dopamine receptor (Human)	BDBM50216051 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES Show InChI	GoogleScholar	UniChem		1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(1B) dopamine receptor (Human)	BDBM50216051 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES Show InChI	GoogleScholar	UniChem		1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM50216051 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES Show InChI	GoogleScholar	UniChem		2.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50216051 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES Show InChI	GoogleScholar	UniChem		2.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50216051 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES Show InChI	GoogleScholar	UniChem		2.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Human)	BDBM50216051 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM50216051 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50216051 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50216051 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair