BDBM50219850 (S)-1-(2-((2-(3-(2,4-dimethylbenzylamino)-1-(tert-butylamino)-1-oxopropan-2-ylamino)-2-oxoethyl)carbamoyl)-4-(trifluoromethyl)phenyl)-3-isopropylurea::CHEMBL247455
SMILES CC(C)NC(=O)Nc1ccc(cc1C(=O)NCC(=O)N[C@@H](CNCc1ccc(C)cc1C)C(=O)NC(C)(C)C)C(F)(F)F
InChI Key InChIKey=AWJUKDQERXTXHY-DEOSSOPVSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50219850
Affinity DataIC50: 240nMAssay Description:Antagonist activity at CCR2 in human PBMCs assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Antagonist activity at CCR2 in THP1 cells assessed as inhibition of MCP1-induced Ca2+ fluxMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Displacement of [125]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]Eotaxin from human CCR3 expressed in CHO cellsMore data for this Ligand-Target Pair