BDBM50224427 CHEMBL241117::N-[(3R)-6-benzyl-2-oxoazepan-3-yl]-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide

SMILES O=C(N[C@@H]1CCC(Cc2ccccc2)CNC1=O)N1CCC(CC1)n1c2cccnc2[nH]c1=O

InChI Key InChIKey=AKEVIWRLWQZPHU-ROPPNANJSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50224427   

TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50224427(CHEMBL241117 | N-[(3R)-6-benzyl-2-oxoazepan-3-yl]-...)
Affinity DataKi:  610nMAssay Description:Displacement of [125I]CGPR from human CL receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50224427(CHEMBL241117 | N-[(3R)-6-benzyl-2-oxoazepan-3-yl]-...)
Affinity DataIC50:  920nMAssay Description:Antagonist activity at human CL receptor expressed in E10 cells assessed as CGRP-stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed