BDBM50227519 4-(6,7-dimethoxyquinazolin-4-ylamino)phenol::CHEMBL405130::CHEMBL555201::US10548897, Compound 7::WHI-P131

SMILES: COc1cc2ncnc(Nc3ccc(O)cc3)c2cc1OC

InChI Key: InChIKey=HOZUXBLMYUPGPZ-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50227519   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinase suppressor of Ras 2 (Human)	BDBM50227519 (CHEMBL405130 | CHEMBL555201 | 4-(6,7-dimethoxyquin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ALK tyrosine kinase receptor (Human)	BDBM50227519 (CHEMBL405130 | CHEMBL555201 | 4-(6,7-dimethoxyquin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50227519 (CHEMBL405130 | CHEMBL555201 | 4-(6,7-dimethoxyquin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50227519 (CHEMBL405130 | CHEMBL555201 | 4-(6,7-dimethoxyquin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM50227519 (CHEMBL405130 | CHEMBL555201 | 4-(6,7-dimethoxyquin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK1 (Human)	BDBM50227519 (CHEMBL405130 | CHEMBL555201 | 4-(6,7-dimethoxyquin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50227519 (CHEMBL405130 | CHEMBL555201 | 4-(6,7-dimethoxyquin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM50227519 (CHEMBL405130 | CHEMBL555201 | 4-(6,7-dimethoxyquin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
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