BDBM50231741 2-phenylethynyl-7,8-dihydro-6H-quinolin-5-one::CHEMBL252956

SMILES: O=C1CCCc2nc(ccc12)C#Cc1ccccc1

InChI Key: InChIKey=XOUDFZJCSDKXLG-UHFFFAOYSA-N

Data: 1 KI  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50231741   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Human)	BDBM50231741 (2-phenylethynyl-7,8-dihydro-6H-quinolin-5-one | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50231741 (2-phenylethynyl-7,8-dihydro-6H-quinolin-5-one | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	172	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50231741 (2-phenylethynyl-7,8-dihydro-6H-quinolin-5-one | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	34	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50231741 (2-phenylethynyl-7,8-dihydro-6H-quinolin-5-one | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50231741 (2-phenylethynyl-7,8-dihydro-6H-quinolin-5-one | CH...) Show SMILES Show InChI	GoogleScholar	UniChem		800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair