BDBM50241580 CHEMBL4089083

SMILES O\N=c1/cc(oc2ccc(CCCN3CCOCC3)cc12)-c1cc2sccc2cn1

InChI Key InChIKey=ZTEDNASHAWNBKQ-NCELDCMTSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50241580   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241580(CHEMBL4089083)
Affinity DataEC50:  79nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241580(CHEMBL4089083)
Affinity DataEC50: >1.50E+4nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing chimeric G protein assessed as increase in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241580(CHEMBL4089083)
Affinity DataEC50:  47nMAssay Description:Positive allosteric modulation of rat mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed