BDBM50243980 3-(N-Methyl-1H-indol-3-yl)-4-(3,4,5-trimethoxyphenyl)-1,5-dihydro-2H-pyrrole-2-one::CHEMBL509435

SMILES: COc1cc(cc(OC)c1OC)C1=C(C(=O)NC1)c1cn(C)c2ccccc12

InChI Key: InChIKey=DUPIINAVKMGMHG-UHFFFAOYSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50243980   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B (Human)	BDBM50243980 (3-(N-Methyl-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 3 (Human)	BDBM50243980 (3-(N-Methyl-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin receptor (Human)	BDBM50243980 (3-(N-Methyl-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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NUAK family SNF1-like kinase 1 (Human)	BDBM50243980 (3-(N-Methyl-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50243980 (3-(N-Methyl-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM50243980 (3-(N-Methyl-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 4 (Human)	BDBM50243980 (3-(N-Methyl-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Focal adhesion kinase 1 (Human)	BDBM50243980 (3-(N-Methyl-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50243980 (3-(N-Methyl-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50243980 (3-(N-Methyl-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM50243980 (3-(N-Methyl-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK4 (Human)	BDBM50243980 (3-(N-Methyl-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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