BDBM50244031 3-(1H-Indol-3-yl)-4-(4-methoxyphenyl)-1,5-dihydro-2H-pyrrole-2-one::CHEMBL452812

SMILES: COc1ccc(cc1)C1=C(C(=O)NC1)c1c[nH]c2ccccc12

InChI Key: InChIKey=XIOUIJRUBUIKSA-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50244031   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 3 (Human)	BDBM50244031 (3-(1H-Indol-3-yl)-4-(4-methoxyphenyl)-1,5-dihydro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50244031 (3-(1H-Indol-3-yl)-4-(4-methoxyphenyl)-1,5-dihydro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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NUAK family SNF1-like kinase 1 (Human)	BDBM50244031 (3-(1H-Indol-3-yl)-4-(4-methoxyphenyl)-1,5-dihydro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50244031 (3-(1H-Indol-3-yl)-4-(4-methoxyphenyl)-1,5-dihydro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 4 (Human)	BDBM50244031 (3-(1H-Indol-3-yl)-4-(4-methoxyphenyl)-1,5-dihydro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50244031 (3-(1H-Indol-3-yl)-4-(4-methoxyphenyl)-1,5-dihydro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50244031 (3-(1H-Indol-3-yl)-4-(4-methoxyphenyl)-1,5-dihydro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK4 (Human)	BDBM50244031 (3-(1H-Indol-3-yl)-4-(4-methoxyphenyl)-1,5-dihydro-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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