BDBM50244439 (2R,3S)-4-(2,3-dichlorophenylsulfonyl)-2,3-dihydroxy-N-((R)-6-(piperidin-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-yl)butanamide::CHEMBL488501

SMILES O[C@H](CS(=O)(=O)c1cccc(Cl)c1Cl)[C@@H](O)C(=O)N[C@@H]1CCCc2cc(CN3CCCCC3)ccc12

InChI Key InChIKey=NPGZSUFBJBAYBE-TZBSWOFLSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50244439   

TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50244439((2R,3S)-4-(2,3-dichlorophenylsulfonyl)-2,3-dihydro...)
Affinity DataKi:  12.7nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in clone CHO-D-/aequorin cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50244439((2R,3S)-4-(2,3-dichlorophenylsulfonyl)-2,3-dihydro...)
Affinity DataIC50:  9.90nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in clone CHO-D-/aequorin cells by aquerin based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Oryctolagus cuniculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50244439((2R,3S)-4-(2,3-dichlorophenylsulfonyl)-2,3-dihydro...)
Affinity DataIC50:  141nMAssay Description:Antagonist activity at rabbit bradykinin B1 receptor expressed in clone CHO-D-/aequorin cells by aquerin based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed