BDBM50245193 (1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazol-4-yl)(4-(quinolin-3-yl)piperazin-1-yl)methanone::CHEMBL453083::CHEMBL503822

SMILES CCOc1cccc(c1)-n1cc(nc1-c1ccc(C)cc1)C(=O)N1CCN(CC1)c1cnc2ccccc2c1

InChI Key InChIKey=CXLIEBRFLLQFMR-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50245193   

TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50245193((1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazol-4-yl)(4-...)
Affinity DataEC50:  0.730nMAssay Description:Agonist activity against human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50245193((1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazol-4-yl)(4-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CCK2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50245193((1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazol-4-yl)(4-...)
Affinity DataEC50:  0.730nMAssay Description:Agonist activity at human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50245193((1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazol-4-yl)(4-...)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50245193((1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazol-4-yl)(4-...)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of human CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50245193((1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazol-4-yl)(4-...)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity against mouse CCK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed