BDBM50247157 (3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)phenyl)pyridin-2-yl)(4-(4-fluorophenylamino)piperidin-1-yl)methanone::CHEMBL473921::{3-[4-((3R,5S)-3,5-Dimethyl-piperazin-1-ylmethyl)-phenyl]-pyridin-2-yl}-[4-(4-fluoro-phenylamino)-piperidin-1-yl]-methanone

SMILES: C[C@H]1CN(Cc2ccc(cc2)-c2cccnc2C(=O)N2CCC(CC2)Nc2ccc(F)cc2)C[C@@H](C)N1

InChI Key: InChIKey=CYEIOVYZTVJICS-UHFFFAOYSA-N

Data: 14 IC50  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50247157   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 3A4 (Human)	BDBM50247157 ((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50247157 ((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Growth hormone secretagogue receptor type 1 (Human)	BDBM50247157 ((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
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Motilin receptor (Human)	BDBM50247157 ((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.98	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50247157 ((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50247157 ((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50247157 ((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50247157 ((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50247157 ((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50247157 ((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Motilin receptor (Human)	BDBM50247157 ((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	19.9	n/a	n/a	n/a	n/a
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Growth hormone secretagogue receptor type 1 (Human)	BDBM50247157 ((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50247157 ((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50247157 ((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50247157 ((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50247157 ((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50247157 ((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50247157 ((3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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