BDBM50247539 CHEMBL472915::N-((3S,5S)-1-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-5-(hydroxycarbamoyl)pyrrolidin-3-yl)nicotinamide::N-((3S,5S)-1-(3-(3,4-dimethoxyphenyl)acryloyl)-5-(hydroxycarbamoyl)pyrrolidin-3-yl)nicotinamide

SMILES: COc1ccc(\C=C\C(=O)N2C[C@H](C[C@H]2C(=O)NO)NC(=O)c2cccnc2)cc1OC

InChI Key: InChIKey=AKOSAZUQCGCWJD-UHFFFAOYSA-N

Data: 14 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50247539   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Human)	BDBM50247539 (N-((3S,5S)-1-((E)-3-(3,4-dimethoxyphenyl)acryloyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	266	n/a	n/a	n/a	n/a	n/a	n/a
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Matrix metalloproteinase-9 (Human)	BDBM50247539 (N-((3S,5S)-1-((E)-3-(3,4-dimethoxyphenyl)acryloyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM50247539 (N-((3S,5S)-1-((E)-3-(3,4-dimethoxyphenyl)acryloyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aminopeptidase N (Human)	BDBM50247539 (N-((3S,5S)-1-((E)-3-(3,4-dimethoxyphenyl)acryloyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.42E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM50247539 (N-((3S,5S)-1-((E)-3-(3,4-dimethoxyphenyl)acryloyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aminopeptidase N (Human)	BDBM50247539 (N-((3S,5S)-1-((E)-3-(3,4-dimethoxyphenyl)acryloyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.42E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM50247539 (N-((3S,5S)-1-((E)-3-(3,4-dimethoxyphenyl)acryloyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aminopeptidase N (Human)	BDBM50247539 (N-((3S,5S)-1-((E)-3-(3,4-dimethoxyphenyl)acryloyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.42E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM50247539 (N-((3S,5S)-1-((E)-3-(3,4-dimethoxyphenyl)acryloyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aminopeptidase N (Pig)	BDBM50247539 (N-((3S,5S)-1-((E)-3-(3,4-dimethoxyphenyl)acryloyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM50247539 (N-((3S,5S)-1-((E)-3-(3,4-dimethoxyphenyl)acryloyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM50247539 (N-((3S,5S)-1-((E)-3-(3,4-dimethoxyphenyl)acryloyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Human)	BDBM50247539 (N-((3S,5S)-1-((E)-3-(3,4-dimethoxyphenyl)acryloyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aminopeptidase N (Pig)	BDBM50247539 (N-((3S,5S)-1-((E)-3-(3,4-dimethoxyphenyl)acryloyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.17E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair