BDBM50247868 2-(3-Chloro-4-fluorophenyl)isothiazol-3(2H)-one::CHEMBL510900

SMILES Fc1ccc(cc1Cl)-n1sccc1=O

InChI Key InChIKey=OOOJWRSQJXGEDS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50247868   

TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50247868(2-(3-Chloro-4-fluorophenyl)isothiazol-3(2H)-one | ...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human recombinant HAT PCAFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Horizon Discovery

Curated by ChEMBL
LigandPNGBDBM50247868(2-(3-Chloro-4-fluorophenyl)isothiazol-3(2H)-one | ...)
Affinity DataIC50:  6.10E+3nMAssay Description:Binding affinity to GST-tagged Pin1 (unknown origin) by SPR spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed