BDBM50058759 CHEMBL436559::CHEMBL462831::Cariporide::N-(4-Isopropyl-3-methanesulfonyl-benzoyl)-guanidine (Cariporide)::N-(4-Isopropyl-3-methanesulfonyl-benzoyl)-guanidine(Cariporide)::N-(4-isopropyl-3-methanesulfonyl-benzoyl)-guanidine::N-(diaminomethylene)-4-isopropyl-3-(methylsulfonyl)benzamide

SMILES: CC(C)c1ccc(cc1S(C)(=O)=O)C(=O)NC(N)=N

InChI Key: InChIKey=IWXNYAIICFKCTM-UHFFFAOYSA-N

Data: 17 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50058759   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/hydrogen exchanger 1 (Human)	BDBM50058759 (CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sodium/hydrogen exchanger 1 (Rat)	BDBM50058759 (CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 1 (Rat)	BDBM50058759 (CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sodium/hydrogen exchanger 1 (Rat)	BDBM50058759 (CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30.7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 1 (Rat)	BDBM50058759 (CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 1 (Human)	BDBM50058759 (CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 1 (Rat)	BDBM50058759 (CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 1 (Human)	BDBM50058759 (CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium/hydrogen exchanger 2 (Human)	BDBM50058759 (CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 1 (Human)	BDBM50058759 (CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 1 (Human)	BDBM50058759 (CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 1 (Human)	BDBM50058759 (CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 2 (Human)	BDBM50058759 (CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium/hydrogen exchanger 3 (Human)	BDBM50058759 (CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium/hydrogen exchanger 5 (Human)	BDBM50058759 (CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 1 (Human)	BDBM50058759 (CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 2 (Human)	BDBM50058759 (CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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