BDBM50248476 CHEMBL491316::N-hydroxy-3-(2-phenethyl-1-(2-(pyrrolidin-1-yl)ethyl)-1H-benzo[d]imidazol-5-yl)acrylamide::N-hydroxy-3-[2-phenethyl-1-(2-pyrrolidin-1-ylethyl)-1H-benzimidazol-5-yl]acrylamide::SB-639::US10201527, Compound 72::US10736881, Compound 72::US8551988, 72

SMILES: ONC(=O)\C=C\c1ccc2n(CCN3CCCC3)c(CCc3ccccc3)nc2c1

InChI Key: InChIKey=RCDIZKAYZBEALO-UHFFFAOYSA-N

Data: 19 KI  5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50248476   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 1 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Histone deacetylase 1 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 1 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Histone deacetylase 1 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 4 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 4 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 1 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 3 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 11 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone deacetylase 11 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 5 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Histone deacetylase 5 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 9 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Polyamine deacetylase HDAC10 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Polyamine deacetylase HDAC10 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 6 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Histone deacetylase 6 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 2 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Histone deacetylase 8 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Human)	BDBM50248476 (US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...) Show SMILES Show InChI	GoogleScholar	UniChem		95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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