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BDBM50248764 2-bromo-4-(6,7-dimethoxyquinazolin-4-ylamino)phenol::CHEMBL473773::WHI-P154

SMILES: COc1cc2ncnc(Nc3ccc(O)c(Br)c3)c2cc1OC

InChI Key: InChIKey=CBIAKDAYHRWZCU-UHFFFAOYSA-N

Data: 3 IC50 2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50248764
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Human)	BDBM50248764 (WHI-P154 \| 2-bromo-4-(6,7-dimethoxyquinazolin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50248764 (WHI-P154 \| 2-bromo-4-(6,7-dimethoxyquinazolin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	189	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Human)	BDBM50248764 (WHI-P154 \| 2-bromo-4-(6,7-dimethoxyquinazolin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.08E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM50248764 (WHI-P154 \| 2-bromo-4-(6,7-dimethoxyquinazolin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Human)	BDBM50248764 (WHI-P154 \| 2-bromo-4-(6,7-dimethoxyquinazolin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair