BDBM50249150 8,15-dimethyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2.0^{2,7}.0^{9,14}]hexadeca-2,4,6,9(14),10,12-hexaene-15-carboxamide::CHEMBL474189

SMILES: CC1(CC2(C)c3ccccc3C1c1ccccc21)C(=O)Nc1nccs1

InChI Key:

Data: 6 KI  12 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50249150   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Human)	BDBM50249150 (8,15-dimethyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	117	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50249150 (8,15-dimethyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50249150 (8,15-dimethyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	117	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50249150 (8,15-dimethyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	121	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50249150 (8,15-dimethyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50249150 (8,15-dimethyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.30	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50249150 (8,15-dimethyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.30	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50249150 (8,15-dimethyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.30	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50249150 (8,15-dimethyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	14.7	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50249150 (8,15-dimethyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	14.7	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50249150 (8,15-dimethyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.30	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50249150 (8,15-dimethyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50249150 (8,15-dimethyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2...) Show SMILES Show InChI	GoogleScholar	UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50249150 (8,15-dimethyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2...) Show SMILES Show InChI	GoogleScholar	UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50249150 (8,15-dimethyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2...) Show SMILES Show InChI	GoogleScholar	UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Progesterone receptor (Human)	BDBM50249150 (8,15-dimethyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2...) Show SMILES Show InChI	GoogleScholar	UniChem		31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM50249150 (8,15-dimethyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2...) Show SMILES Show InChI	GoogleScholar	UniChem		2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50249150 (8,15-dimethyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2...) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair