BDBM50249319 2-(2-aminoethylamino)-4-(3-(trifluoromethyl)phenylamino)pyrimidine-5-carboxamide::CHEMBL471901

SMILES: NCCNc1ncc(C(N)=O)c(Nc2cccc(c2)C(F)(F)F)n1

InChI Key: InChIKey=FQNFLNSVHWCZML-UHFFFAOYSA-N

Data: 13 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50249319   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium/calmodulin-dependent protein kinase type 1D (Human)	BDBM50249319 (CHEMBL471901 | 2-(2-aminoethylamino)-4-(3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	456	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM50249319 (CHEMBL471901 | 2-(2-aminoethylamino)-4-(3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
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Calcium/calmodulin-dependent protein kinase type 1D (Human)	BDBM50249319 (CHEMBL471901 | 2-(2-aminoethylamino)-4-(3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	432	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ZAP-70 (Human)	BDBM50249319 (CHEMBL471901 | 2-(2-aminoethylamino)-4-(3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine--tRNA ligase (Human)	BDBM50249319 (CHEMBL471901 | 2-(2-aminoethylamino)-4-(3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM50249319 (CHEMBL471901 | 2-(2-aminoethylamino)-4-(3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM50249319 (CHEMBL471901 | 2-(2-aminoethylamino)-4-(3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM50249319 (CHEMBL471901 | 2-(2-aminoethylamino)-4-(3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C epsilon type (Human)	BDBM50249319 (CHEMBL471901 | 2-(2-aminoethylamino)-4-(3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ZAP-70 (Human)	BDBM50249319 (CHEMBL471901 | 2-(2-aminoethylamino)-4-(3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ITK/TSK (Human)	BDBM50249319 (CHEMBL471901 | 2-(2-aminoethylamino)-4-(3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM50249319 (CHEMBL471901 | 2-(2-aminoethylamino)-4-(3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM50249319 (CHEMBL471901 | 2-(2-aminoethylamino)-4-(3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
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