BDBM50255286 CHEMBL481614::N-(3,5-dichlorophenylsulfonyl)-3-(1-(3,4-difluorobenzyl)-3a-methyl-2-oxo-2,3,3a,4,5,6-hexahydro-1H-indol-7-yl)acrylamide

SMILES CC12CC(=O)N(Cc3ccc(F)c(F)c3)C1=C(CCC2)\C=C\C(=O)NS(=O)(=O)c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=AIEHEPFQGINRGI-FNORWQNLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50255286   

TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255286(CHEMBL481614 | N-(3,5-dichlorophenylsulfonyl)-3-(1...)
Affinity DataIC50:  3.20nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO-K1 cells assessed as reversal of inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255286(CHEMBL481614 | N-(3,5-dichlorophenylsulfonyl)-3-(1...)
Affinity DataIC50:  5.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed