BDBM50257900 (1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopropyl-3-(tetrahydro-2H-thiopyran-4-ylamino)cyclopentanecarboxamide::CHEMBL521697

SMILES CC(C)[C@@]1(CC[C@H](C1)NC1CCSCC1)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=NKLAOPBORRSLGF-CTNGQTDRSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257900   

TargetC-C motif chemokine 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50257900((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)
Affinity DataKi:  31nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))TBA
LigandPNGBDBM50257900((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)
Affinity DataIC50:  36nMAssay Description:Antagonist activity at CCR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetC-C chemokine receptor type 2(Homo sapiens (Human))TBA
LigandPNGBDBM50257900((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)
Affinity DataIC50:  22nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed