BDBM50259637 3-{[2-(2-Furyl)pyridin-4-yl]amino}-4-{[(1R)-1-phenylethyl]amino}cyclobut-3-ene-1,2-dione::CHEMBL519113

SMILES: C[C@@H](Nc1c(Nc2ccnc(c2)-c2ccco2)c(=O)c1=O)c1ccccc1

InChI Key: InChIKey=WSGJNLVHAHAWQS-UHFFFAOYSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50259637   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C alpha type (Human)	BDBM50259637 (3-{[2-(2-Furyl)pyridin-4-yl]amino}-4-{[(1R)-1-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit alpha (Human)	BDBM50259637 (3-{[2-(2-Furyl)pyridin-4-yl]amino}-4-{[(1R)-1-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50259637 (3-{[2-(2-Furyl)pyridin-4-yl]amino}-4-{[(1R)-1-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Rho-associated protein kinase 1 (Human)	BDBM50259637 (3-{[2-(2-Furyl)pyridin-4-yl]amino}-4-{[(1R)-1-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-1 (Human)	BDBM50259637 (3-{[2-(2-Furyl)pyridin-4-yl]amino}-4-{[(1R)-1-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50259637 (3-{[2-(2-Furyl)pyridin-4-yl]amino}-4-{[(1R)-1-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Casein kinase I isoform gamma-1 (Human)	BDBM50259637 (3-{[2-(2-Furyl)pyridin-4-yl]amino}-4-{[(1R)-1-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 1 (Human)	BDBM50259637 (3-{[2-(2-Furyl)pyridin-4-yl]amino}-4-{[(1R)-1-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Fyn (Human)	BDBM50259637 (3-{[2-(2-Furyl)pyridin-4-yl]amino}-4-{[(1R)-1-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50259637 (3-{[2-(2-Furyl)pyridin-4-yl]amino}-4-{[(1R)-1-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha (Human)	BDBM50259637 (3-{[2-(2-Furyl)pyridin-4-yl]amino}-4-{[(1R)-1-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
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MAP kinase-activated protein kinase 2 (Human)	BDBM50259637 (3-{[2-(2-Furyl)pyridin-4-yl]amino}-4-{[(1R)-1-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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