BDBM50265098 4-(4-(2-(cyclopropylmethoxy)-5-(methylsulfonyl)benzoyl)piperazin-1-yl)-3-fluorobenzonitrile::CHEMBL497999

SMILES: CS(=O)(=O)c1ccc(OCC2CC2)c(c1)C(=O)N1CCN(CC1)c1ccc(cc1F)C#N

InChI Key: InChIKey=IOSCQMWDOQVSFE-UHFFFAOYSA-N

Data: 7 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50265098   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Human)	BDBM50265098 (4-(4-(2-(cyclopropylmethoxy)-5-(methylsulfonyl)ben...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50265098 (4-(4-(2-(cyclopropylmethoxy)-5-(methylsulfonyl)ben...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50265098 (4-(4-(2-(cyclopropylmethoxy)-5-(methylsulfonyl)ben...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50265098 (4-(4-(2-(cyclopropylmethoxy)-5-(methylsulfonyl)ben...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50265098 (4-(4-(2-(cyclopropylmethoxy)-5-(methylsulfonyl)ben...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50265098 (4-(4-(2-(cyclopropylmethoxy)-5-(methylsulfonyl)ben...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50265098 (4-(4-(2-(cyclopropylmethoxy)-5-(methylsulfonyl)ben...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium- and chloride-dependent glycine transporter 2 (Human)	BDBM50265098 (4-(4-(2-(cyclopropylmethoxy)-5-(methylsulfonyl)ben...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
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Sodium- and chloride-dependent glycine transporter 1 (Human)	BDBM50265098 (4-(4-(2-(cyclopropylmethoxy)-5-(methylsulfonyl)ben...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50265098 (4-(4-(2-(cyclopropylmethoxy)-5-(methylsulfonyl)ben...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
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