BDBM50266416 CHEMBL458224::N-[2-(3,5-Dimethylpyrazol-1-yl)-6-(2-(R)-methoxymethylpyrrolidin-1-yl)pyrimidin-4-yl]acetamide

SMILES: COC[C@H]1CCCN1c1cc(NC(C)=O)nc(n1)-n1nc(C)cc1C

InChI Key: InChIKey=FGADYIBOWLXZLA-UHFFFAOYSA-N

Data: 6 KI  6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50266416   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2a (Human)	BDBM50266416 (N-[2-(3,5-Dimethylpyrazol-1-yl)-6-(2-(R)-methoxyme...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50266416 (N-[2-(3,5-Dimethylpyrazol-1-yl)-6-(2-(R)-methoxyme...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50266416 (N-[2-(3,5-Dimethylpyrazol-1-yl)-6-(2-(R)-methoxyme...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50266416 (N-[2-(3,5-Dimethylpyrazol-1-yl)-6-(2-(R)-methoxyme...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50266416 (N-[2-(3,5-Dimethylpyrazol-1-yl)-6-(2-(R)-methoxyme...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50266416 (N-[2-(3,5-Dimethylpyrazol-1-yl)-6-(2-(R)-methoxyme...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A2a (Human)	BDBM50266416 (N-[2-(3,5-Dimethylpyrazol-1-yl)-6-(2-(R)-methoxyme...) Show SMILES Show InChI	GoogleScholar	UniChem		4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A2a (Human)	BDBM50266416 (N-[2-(3,5-Dimethylpyrazol-1-yl)-6-(2-(R)-methoxyme...) Show SMILES Show InChI	GoogleScholar	UniChem		15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A3 (Human)	BDBM50266416 (N-[2-(3,5-Dimethylpyrazol-1-yl)-6-(2-(R)-methoxyme...) Show SMILES Show InChI	GoogleScholar	UniChem		19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A2a (Rat)	BDBM50266416 (N-[2-(3,5-Dimethylpyrazol-1-yl)-6-(2-(R)-methoxyme...) Show SMILES Show InChI	GoogleScholar	UniChem		48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A2b (Human)	BDBM50266416 (N-[2-(3,5-Dimethylpyrazol-1-yl)-6-(2-(R)-methoxyme...) Show SMILES Show InChI	GoogleScholar	UniChem		145	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A1 (Human)	BDBM50266416 (N-[2-(3,5-Dimethylpyrazol-1-yl)-6-(2-(R)-methoxyme...) Show SMILES Show InChI	GoogleScholar	UniChem		162	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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