BDBM50267480 4-{[(4-Hydroxy-5-propoxy-pyridin-2-ylmethyl)-amino]-methylene}-6-iodo-4H-isoquinoline-1,3-dione::CHEMBL477064

SMILES: CCCOc1cnc(CNC=C2C(=O)NC(=O)c3ccc(I)cc23)cc1O

InChI Key: InChIKey=DXMZEMWEDCPBNA-UHFFFAOYSA-N

Data: 10 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50267480   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM50267480 (4-{[(4-Hydroxy-5-propoxy-pyridin-2-ylmethyl)-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-T1/Cyclin-dependent kinase 9 (Human)	BDBM50267480 (4-{[(4-Hydroxy-5-propoxy-pyridin-2-ylmethyl)-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Human)	BDBM50267480 (4-{[(4-Hydroxy-5-propoxy-pyridin-2-ylmethyl)-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM50267480 (4-{[(4-Hydroxy-5-propoxy-pyridin-2-ylmethyl)-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
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CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Human)	BDBM50267480 (4-{[(4-Hydroxy-5-propoxy-pyridin-2-ylmethyl)-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM50267480 (4-{[(4-Hydroxy-5-propoxy-pyridin-2-ylmethyl)-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 5 activator 1 (Human)	BDBM50267480 (4-{[(4-Hydroxy-5-propoxy-pyridin-2-ylmethyl)-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM50267480 (4-{[(4-Hydroxy-5-propoxy-pyridin-2-ylmethyl)-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1 (Human)	BDBM50267480 (4-{[(4-Hydroxy-5-propoxy-pyridin-2-ylmethyl)-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 4 (Human)	BDBM50267480 (4-{[(4-Hydroxy-5-propoxy-pyridin-2-ylmethyl)-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
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