BDBM50277529 4'-(2-{[(2R)-2-Hydroxy-2-phenylethyl]amino}ethyl)-3-(isopropylamino)-N-(methylsulfonyl)biphenyl-4-carboxamide Dihydrochloride::CHEMBL471060

SMILES CC(C)Nc1cc(ccc1C(=O)NS(C)(=O)=O)-c1ccc(CCNC[C@H](O)c2ccccc2)cc1

InChI Key InChIKey=FEQQLEGJQNYEQY-SANMLTNESA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50277529   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50277529(4'-(2-{[(2R)-2-Hydroxy-2-phenylethyl]amino}ethyl)-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Canis familiaris)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50277529(4'-(2-{[(2R)-2-Hydroxy-2-phenylethyl]amino}ethyl)-...)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at dog recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50277529(4'-(2-{[(2R)-2-Hydroxy-2-phenylethyl]amino}ethyl)-...)
Affinity DataEC50:  260nMAssay Description:Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50277529(4'-(2-{[(2R)-2-Hydroxy-2-phenylethyl]amino}ethyl)-...)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed