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BDBM50279852 10H-Phenoxazine-1-carboxylic acid::CHEMBL274905

SMILES: OC(=O)c1cccc2Oc3ccccc3Nc12

InChI Key: InChIKey=OPXLFVRTNVYKMK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279852   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (Human))
BDBM50279852
PNG
(10H-Phenoxazine-1-carboxylic acid | CHEMBL274905)
Show SMILES OC(=O)c1cccc2Oc3ccccc3Nc12
Show InChI InChI=1S/C13H9NO3/c15-13(16)8-4-3-7-11-12(8)14-9-5-1-2-6-10(9)17-11/h1-7,14H,(H,15,16)
PDB
MMDB

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Article
n/an/a 610n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [14C]-arachidonic acid conversion to 5-HETE by broken cell 5-lipoxygenase in vitro (guinea pig PMN)


Bioorg Med Chem Lett 1: 107-110 (1991)


Article DOI: 10.1016/S0960-894X(00)80241-3
BindingDB Entry DOI: 10.7270/Q2DF6R3J
More data for this
Ligand-Target Pair