BDBM50280469 CHEMBL346633::[(2R,3R)-2-(2,2-Diphenyl-ethyl)-1-aza-bicyclo[2.2.2]oct-3-yl]-(2-methyl-benzyl)-amine

SMILES Cc1ccccc1CN[C@@H]1C2CCN(CC2)[C@@H]1C(c1ccccc1)c1ccccc1

InChI Key InChIKey=KHWRHXNNDGPGGG-VSGBNLITSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280469   

TargetSubstance-P receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50280469(CHEMBL346633 | [(2R,3R)-2-(2,2-Diphenyl-ethyl)-1-a...)
Affinity DataIC50:  700nMAssay Description:Binding affinity towards Tachykinin receptor 1 in rat cerebral cortex membranes was determined by using 125 [I]-BHSP as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50280469(CHEMBL346633 | [(2R,3R)-2-(2,2-Diphenyl-ethyl)-1-a...)
Affinity DataIC50:  227nMAssay Description:Binding affinity towards Tachykinin receptor 1 binding in guinea pig cerebral cortex membranes was determined using [3H]SP as the radioligandMore data for this Ligand-Target Pair
In DepthDetails Article