BDBM50280470 Benzyl-[(2R,3R)-2-(2,2-diphenyl-ethyl)-1-aza-bicyclo[2.2.2]oct-3-yl]-amine::CHEMBL357717

SMILES C(N[C@@H]1C2CCN(CC2)[C@@H]1C(c1ccccc1)c1ccccc1)c1ccccc1

InChI Key InChIKey=SVHVLAGNGAWUQU-KAYWLYCHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280470   

TargetSubstance-P receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50280470(Benzyl-[(2R,3R)-2-(2,2-diphenyl-ethyl)-1-aza-bicyc...)
Affinity DataIC50:  2.00E+3nMAssay Description:Binding affinity towards Tachykinin receptor 1 in rat cerebral cortex membranes was determined by using 125 [I]-BHSP as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50280470(Benzyl-[(2R,3R)-2-(2,2-diphenyl-ethyl)-1-aza-bicyc...)
Affinity DataIC50:  52nMAssay Description:Binding affinity towards Tachykinin receptor 1 binding in guinea pig cerebral cortex membranes was determined using [3H]SP as the radioligandMore data for this Ligand-Target Pair
In DepthDetails Article