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BDBM50283319 2-Butyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbonylaminosulphonyl)-biphenyl-4-ylmethyl)-6-(isopropyl-methyl-aminocarbonylamino)-3H-quinazolin-4-one::CHEMBL306362
SMILES: CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCC1CC1
InChI Key: InChIKey=COFPUUSXDAODDA-UHFFFAOYSA-N
Data: 6 IC50
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Type-2 angiotensin II receptor (Rat) | BDBM50283319![]() (2-Butyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbo...) | GoogleScholar | UniChem | n/a | n/a | 0.360 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Type-1 angiotensin II receptor (Rabbit) | BDBM50283319![]() (2-Butyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbo...) | GoogleScholar | UniChem | n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Type-2 angiotensin II receptor (Human) | BDBM50283319![]() (2-Butyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbo...) | GoogleScholar | UniChem | n/a | n/a | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Type-1 angiotensin II receptor (Human) | BDBM50283319![]() (2-Butyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbo...) | GoogleScholar | UniChem | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Type-2 angiotensin II receptor (Rat) | BDBM50283319![]() (2-Butyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbo...) | GoogleScholar | UniChem | n/a | n/a | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Type-1 angiotensin II receptor A/B (Rat) | BDBM50283319![]() (2-Butyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbo...) | GoogleScholar | UniChem | n/a | n/a | 0.230 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||