BindingDB logo
myBDB logout

BDBM50283319 2-Butyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbonylaminosulphonyl)-biphenyl-4-ylmethyl)-6-(isopropyl-methyl-aminocarbonylamino)-3H-quinazolin-4-one::CHEMBL306362

SMILES: CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCC1CC1

InChI Key: InChIKey=COFPUUSXDAODDA-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50283319   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Type-2 angiotensin II receptor


(Rat)
BDBM50283319
PNG
(2-Butyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbo...)
GoogleScholar
UniChem
n/an/a 0.360n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Rabbit)
BDBM50283319
PNG
(2-Butyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbo...)
GoogleScholar
UniChem
n/an/a 0.130n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Type-2 angiotensin II receptor


(Human)
BDBM50283319
PNG
(2-Butyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbo...)
GoogleScholar
UniChem
n/an/a 7.80n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor


(Human)
BDBM50283319
PNG
(2-Butyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbo...)
GoogleScholar
UniChem
n/an/a 1.20n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Type-2 angiotensin II receptor


(Rat)
BDBM50283319
PNG
(2-Butyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbo...)
GoogleScholar
UniChem
n/an/a 0.290n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Type-1 angiotensin II receptor A/B


(Rat)
BDBM50283319
PNG
(2-Butyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbo...)
GoogleScholar
UniChem
n/an/a 0.230n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair