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BDBM50289605 4-Furan-2-yl-6-furan-3-yl-2-(4-methyl-piperazin-1-yl)-pyrimidine::CHEMBL42061

SMILES: CN1CCN(CC1)c1nc(cc(n1)-c1ccco1)-c1ccoc1

InChI Key: InChIKey=AKMGJJTVIPHEOZ-UHFFFAOYSA-N

Data: 2 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289605   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50289605
PNG
(4-Furan-2-yl-6-furan-3-yl-2-(4-methyl-piperazin-1-...)
Show SMILES CN1CCN(CC1)c1nc(cc(n1)-c1ccco1)-c1ccoc1
Show InChI InChI=1S/C17H18N4O2/c1-20-5-7-21(8-6-20)17-18-14(13-4-10-22-12-13)11-15(19-17)16-3-2-9-23-16/h2-4,9-12H,5-8H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
13n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-ketanserin from 5-hydroxytryptamine 2A receptor of rat brain cortex


Bioorg Med Chem Lett 7: 1635-1638 (1997)


Article DOI: 10.1016/S0960-894X(97)00291-6
BindingDB Entry DOI: 10.7270/Q2QZ29ZT
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50289605
PNG
(4-Furan-2-yl-6-furan-3-yl-2-(4-methyl-piperazin-1-...)
Show SMILES CN1CCN(CC1)c1nc(cc(n1)-c1ccco1)-c1ccoc1
Show InChI InChI=1S/C17H18N4O2/c1-20-5-7-21(8-6-20)17-18-14(13-4-10-22-12-13)11-15(19-17)16-3-2-9-23-16/h2-4,9-12H,5-8H2,1H3
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
415n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat brain hippocampus


Bioorg Med Chem Lett 7: 1635-1638 (1997)


Article DOI: 10.1016/S0960-894X(97)00291-6
BindingDB Entry DOI: 10.7270/Q2QZ29ZT
More data for this
Ligand-Target Pair